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Cannabis genetics fundamentally dictate the plant's potential for chemical signatures, including cannabinoid and terpene profiles, and physical traits, such as yield. Cultivators use selective techniques, such as "stacking," to enhance specific compounds. Ultimately, successful cultivation involves balancing superior genetics with environmental "levers" to optimize gene expression and create targeted strains.

Image | adobe.stock/Maksim Kabakou

It’s that time of year again—the Cannabis Science and Technology (CST) top 10 articles from the previous year. CST published a wide variety of content throughout 2025. Here is just a small snippet of some of the top articles that our readers enjoyed. See if any of your favorites made the list!

For cannabis flower, cannabinoids occur at concentrations far too high for traditional spike recovery experiments to meaningfully assess extraction efficiency. Even large spike additions contribute only a small fraction of the total analyte mass, making recovery results insensitive to extraction performance. This article explains why extraction efficiency for cannabinoid methods must instead be established through matrix-exhaustive, sequential extraction studies.

Here, we review the major developments of 2025 impacting the legal cannabis and hemp industries, including state-specific hemp policies, the long-awaited 2024 Farm Bill, and the continuing federal process around cannabis rescheduling. It concludes with what stakeholders should expect as the stage is set for consequential policy activity in 2026.

This article delves into how analytical chemists should approach their work, taking into consideration the context of the analysis and multiple parameters based on the Golden Rectangle of Chemical Analysis to develop and use the appropriate analytical methods.

Our top cannabis news topics this week: President Trump’s executive order on cannabis rescheduling, hemp regulation legislation, NY program using cannabis to reduce opioid use, cannabis genetics and cannabinoid profiles, and the latest cannabis research studies.