Chromatography Techniques

Brian C. Smith, PhD, is Founder, CEO, and Chief Technical Officer of Big Sur Scientific. He is the inventor of the BSS series of patented mid-infrared based cannabis analyzers. Dr. Smith has done pioneering research and published numerous peer-reviewed papers on the application of mid-infrared spectroscopy to cannabis analysis, and sits on the editorial board of Cannabis Science and Technology. He has worked as a laboratory director for a cannabis extractor, as an analytical chemist for Waters Associates and PerkinElmer, and as an analytical instrument salesperson. He has more than 30 years of experience in chemical analysis and has written three books on the subject. Dr. Smith earned his PhD on physical chemistry from Dartmouth College. Direct correspondence to: 

Articles

In part I of this series on statistical concepts related to cannabis analysis, we introduce the normal distribution, standard deviation, and how to calculate precision and accuracy.

Statistics for Cannabis Analysis, Part I: Standard Deviation and Its Relationship to Accuracy and Precision

Patricia Atkins is a Senior Applications Scientist with SPEX CertiPrep and a member of both the AOAC and ASTM committees for cannabis.

What is the overall scope of spectroscopy and how can it be used as a tool to improve analyses?

Examining Energy and Light: Understanding Spectroscopy and Spectrophotometry

We finish looking at liquid chromatography with a deeper examination of the mechanics, physics, and chemistry of different spectrometers that are used in analytical laboratories.

Looking with Light: Understanding Spectrometry

A number of misconceptions people have about how to test, what to test, and when to test in the cannabis industry are dispelled.

Dispelling Cannabis Analysis Myths, Part I

A systematic literature review to identify and compare analytical methods used for the determination of cannabinoids in different matrices using LC-based systems.

Analytical Techniques Used for Analysis of Cannabinoids

A deeper look into the chemistry, physics, and methodology of HPLC methods.

Looking with Light: Breaking Down Liquid Chromatography Method Development

From simple separations to detailed wavelength analysis, we examine the important concepts and techniques needed to make liquid chromatography work its best in the laboratory.

Looking with Light: Understanding the Principles of Analytical Liquid Chromatography

Keystone Labs is an accredited testing facility with a good manufacturing practice (GMP) establishment license. Jodi McDonald, president and founder of Keystone Labs, based in Edmonton Alberta, Canada discusses their role in the industry.

Quality Matters: A Chat with Keystone Labs President, Jodi McDonald

A rapid LC–MS/MS method is presented for the quantitative analysis of 16 cannabinoids in hemp samples with a single dilution protocol.

Rapid Analysis of 16 Major and Minor Cannabinoids in Hemp Using LC–MS/MS with a Single Sample Dilution and Injection

is a Senior Scientist at Agilent Technologies and a Visiting Professor at The Johns Hopkins University School of Medicine in Baltimore, Maryland.

This article focuses on the use of GC–MS for the analysis of derivatized cannabinoids in hempseed oil matrix.