Cannabinoids

Dr. Richard van Breemen from the Department of Pharmaceutical Sciences in the Oregon State University College of Pharmacy discusses his COVID-19 and cannabis research.

This study focuses on a step-by-step optimization of commercial scale preparative HPLC purification of cannabinoids, specifically cannabidiol, starting with stationary reversed-phase screening, followed by method optimization.

It is demonstrated in this paper that cell viability can be used to determine dose and response effects that are important in understanding toxicities and to detect differences in similar hemp products.

Terpenes can be tricky. Although cannabis is heavily regulated, since cannabis-derived terpenes do not contain tetrahydrocannabinol (THC) and other cannabinoids, they are not regulated in the same way that cannabis is.

In this piece, we touch on the benefits and challenges associated with autoflowering genetics, and provide justification for why these unique varietals may be the catalyst for making cannabis medicine more accessible and approachable for the general population.

Gb Sciences, recently announced positive results from a study of its cannabinoid-containing mixtures as a potential treatment for cytokine release syndrome (CRS). With the high rate of transmission of the Omicron variant in multiple countries, Gb Sciences team are working to move quickly through the development stages for this novel CRS therapy.

Dr. Denise Vidot shares some of her research findings that examine the impact of phytocannabinoids on multiple diseases.

Here we take an in-depth exploration of the structure, function, and variation of cannabinoid receptor 1 (CB1R).

This technical piece is focused on the separation of the individual enantiomers of each compound mentioned above, as well as the combined separation of the compounds from each other for a fast, reliable quantification.

Professor Edvinas Orentas clears the air surrounding the stigma of synthetic cannabinoids.

The 5-part program will dive deep into cultivation, extraction, processing, testing, third-party certifications, and more.

Soil, water, and nutrient compositions play important roles in one’s quest to produce ultrapremium flower material; but unequivocally, it is lighting spectrum, coverage, and penetration that have the most influence over the terminal outcome, particularly in controlled environment agriculture.

This article explores what we do and don’t know about the origins of Cannabis ssp. from a botanical perspective and outlines some of the hypotheses proposed to explain the “why” of cannabinoid production in plants and the approaches that researchers are taking to try and answer this elusive question.

A review on a handful of recent articles related to COVID-19 and cannabis as well as an interview with a top medical cannabis expert—Dr. Prakash Nagarkatti.

Op-ed on a new study related to how cannabidiol (CBD) exerts its clinical efficacy.

Ric Cuchetto discusses the technology behind THC remediation and some of the challenges it presents.

This article explores the pros and cons of grinding cannabis prior to extraction along with the effects of particle size.

An interview with Dr. Bonni Goldstein on treating patients during a pandemic, telemedicine, cannabis research, and more.

A rapid LC–MS/MS method is presented for the quantitative analysis of 16 cannabinoids in hemp samples with a single dilution protocol.

This article focuses on the use of GC–MS for the analysis of derivatized cannabinoids in hempseed oil matrix.

A review of the chemical makeup of cannabis extracts and how they affect the human body. From terpenes to cannabinoids, this article takes a deep dive into the chemistry of cannabis extracts.

An interview with an amazing family of four doctors—the Knox Docs—who are key opinion leaders in cannabis therapeutics, endocannabinology, and cannabinoid medicine.

A closer look at some of the current in vitro evidence suggesting that cannabinoids possess potent activity against a range of gram-positive bacteria.

Dr. Linda Klumpers discusses her interest in neuroscience, her most significant work, success stories from Cannify—an online science-matching tool—and more.

This study highlights a potential concern for the quantitation of acid phytocannabinoids.

A large data set from Washington (140,000 flower samples) is scrutinized here for evidence of consistently propagated strains with higher than a 2-to-1 ratio.

Applications of a quantitative mid-infrared spectrometer for hemp farmers, hemp extractors, state regulators, and law enforcement are discussed.

A review of the literature to examine the analgesic properties of cannabis.

Dr. Andrea Holmes discusses how she’s using colorimetric analysis to discover novel minor cannabinoids, the potential role of smartphone compatibility in detection, what’s next for cannabinoid research, and more.