Cannabinoids

Searching for purer, minor cannabinoids is the goal of new extraction research as extractors dig deeper into the diversity of the plant.

The current challenges and future perspectives of the purification of cannabinoids from cannabis extracts are presented in this review article.

The effects of worms consuming cannabis were researched in a experiment showing that that they got the munchies and craved junk food.

To help clinicians and patients navigate cannabinoid-based medications (CBM), Cannabis and Cannabinoid Research published guidelines based on reviews of studies on CBM and chronic pain.

When you think of cannabis, you probably don’t think of horses or the potential medicinal benefit to animals. However, the cannabinoids found in cannabis have been shown to provide similar benefits in animals that are noted with human patients. In this interview, Emma Davis, founder of Mikko’s Choice, delves into how some cannabinoids—such as tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN), and tetrahydrocannabinolic acid (THCA)—have provided medicinal benefits to horses. Davis also discusses her mustang, Mikko, who inspired her to launch her own cannabis and hemp product brand.

On February 13, 2023, the US Drug Enforcement Administration (DEA) declared in a letter that the cannabinoids delta-8 and -9 THCO are both considered controlled substances due to their chemical structures.

Currently in the life cycle of the cannabis industry, it is not obvious where the heavy metal regulatory landscape will end up. Clearly, the big four are not enough, but what is a realistic panel that reflects the real world of cannabinoid production?

In this recent interview, Bruce Kendall and Dr. Hinanit Koltai of the Volcani Institute share the inspiring story of the late Michelle Kendall and how her passion for science and research brought them all together to study medical cannabis as a potential treatment for ovarian cancer.

In the work presented here, the author shares research from collecting reports from the New Jersey State laboratory (the Department of Health’s Environmental and Chemical Laboratory Services), which has conducted testing for the state’s medicinal program. He documented an average variance of 20% in potency levels from different samples of the same test lot.

Dr. Dustin Sulak of Healer.com and Integr8 Health shares some insights from two talks he gave at Cannabis Science Conference East 2022.

A review of the claims that differences in extract type can affect cost, ease of formulation, and the experience of the finished product.

In the work presented here, the authors pursue a more detailed understanding of the naturally rare occurring cannabinoid analogue, hexahydrocannabinol (HHC), by exploring the safety profile using a third-party lab to produce preclinical in vitro safety profile data. The purpose of these studies is to demonstrate HHC as a safe cannabinoid for potential human consumption.

This article examines why we should be studying the cannabinoids beyond THC and CBD in order to explore their potential medical value.

Understanding the biochemical and physical process that comprise and control leaf-level physiology gives us deep insight into the plant, which may convert directly to cultivation practices.

The various extract types are defined so there can be some consensus once and for all.

When a patient isn’t able to access the care or medication that they need in their home country, they aren’t left with much of a choice but to travel to a country that will give them the treatment they need. In part II of this interview series, Nikki Lawley, founder of Nikki and the Plant, LLC, and retired licensed practical nurse (LPN), continues discussing her journey to health, the broken healthcare system hurting medical cannabis patients in the US, and what needs to change to make access better for patients.

Part II of this series reviews the history of vape products, producing cannabis vapes, the myriad of extract types, and how temperature and hardware impact the user experience.

On May 19, 2022 a federal appeals court ruled in a California vaping dispute that delta-8 tetrahydrocannabinol (THC) derived from hemp is “lawful.”

Dr. Woody, chief executive officer of 180 Life Sciences, discusses in this interview the current research surrounding synthetic cannabinoids as a treatment for chronic pain, as well as the development of a new type of medication that would have the potential to offer the benefits of cannabis without any undesirable effects.

The science of cannabis is in its beginning stages and has a large opportunity for growth advancement. Market Manager for Cannabis for Shimadzu, Eberhardt Kuhn, Ph.D., will be presenting two talks for both the hemp and analytical tracks, “Starting with the Roots - the Many Uses of Hemp” and “Delta Dawn - the Next Generation of Cannabinoids?” If you are interested in exploring hemp or cannabidiol (CBD) and other cannabinoids, check out both of these presentations to learn more! In this interview, Kuhn also discusses his interests in the cannabis industry and other presenters at the Cannabis Science Conference (CSC) West taking place in Long Beach, California from May 18–20, 2022.

In part one of this two-part series, we review the history of vape products and their obstacles.

Cannabis Science Conference West, taking place May 18-20 in Long Beach, California, is quickly approaching. The two-day agenda is packed with exciting speakers from around the country as well as many prominent women moving the industry forward. In honor of Women’s History Month, we connected with Dr. Lakisha Jenkins-Samuels, a traditional naturopath, Dr. Lakisha™️.

As time passes and more research comes to light regarding COVID-19, additional research is also needed for cannabis and its various cannabinoids. Through new data, cannabis has shown that it has more to offer than the stigma it has been clouded by. In this interview, Inesa Ponomariovaite, founder of Nesas Hemp and a holistic health coach, discusses the untapped medicinal properties of cannabidiolic acid (CBDA) and cannabigerolic acid (CGBA) for COVID-19 prevention and treatment and why CBDA is the top cannabinoid.

The new processed cannabis products continue to attract consumers—but black market influence causes hesitancy.

Dr. Richard van Breemen from the Department of Pharmaceutical Sciences in the Oregon State University College of Pharmacy discusses his COVID-19 and cannabis research.

This study focuses on a step-by-step optimization of commercial scale preparative HPLC purification of cannabinoids, specifically cannabidiol, starting with stationary reversed-phase screening, followed by method optimization.

It is demonstrated in this paper that cell viability can be used to determine dose and response effects that are important in understanding toxicities and to detect differences in similar hemp products.

Terpenes can be tricky. Although cannabis is heavily regulated, since cannabis-derived terpenes do not contain tetrahydrocannabinol (THC) and other cannabinoids, they are not regulated in the same way that cannabis is.

In this piece, we touch on the benefits and challenges associated with autoflowering genetics, and provide justification for why these unique varietals may be the catalyst for making cannabis medicine more accessible and approachable for the general population.

Gb Sciences, recently announced positive results from a study of its cannabinoid-containing mixtures as a potential treatment for cytokine release syndrome (CRS). With the high rate of transmission of the Omicron variant in multiple countries, Gb Sciences team are working to move quickly through the development stages for this novel CRS therapy.