Cannabinoids

Articles

The 5-part program will dive deep into cultivation, extraction, processing, testing, third-party certifications, and more.

Cannabis Science and Technology® and Nutritional Outlook® Launch Expert-Driven Webcast Series on CBD Quality Control, Testing, and More

Soil, water, and nutrient compositions play important roles in one’s quest to produce ultrapremium flower material; but unequivocally, it is lighting spectrum, coverage, and penetration that have the most influence over the terminal outcome, particularly in controlled environment agriculture.

Lighting: Setting the Stage for Genetic Potential in Cannabis and Hemp

This article explores what we do and don’t know about the origins of Cannabis ssp. from a botanical perspective and outlines some of the hypotheses proposed to explain the “why” of cannabinoid production in plants and the approaches that researchers are taking to try and answer this elusive question.

Back to the Root The Role of Botany and Plant Physiology in Cannabis Testing, Part IV: The Botany of Cannabinoids or Why Do Plants Produce Cannabinoids and What’s in it for Them?

Josh Crossney is the columnist and editor of “Cannabis Crossroads” and a contributing editor to 

 magazine. Crossney is also the president and CEO of Cannabis Science Conference. Direct correspondence to:


A review on a handful of recent articles related to COVID-19 and cannabis as well as an interview with a top medical cannabis expert—Dr. Prakash Nagarkatti.

A Storm of Research Activity into Cannabis and Coronavirus A Closer Look at Expanding Research of Cannabinoids and Terpenes in COVID-19

Op-ed on a new study related to how cannabidiol (CBD) exerts its clinical efficacy.

New Study Links Cannabidiol’s Multitudinous Effects to Disruption of Cholesterol Homeostasis

Ric Cuchetto discusses the technology behind THC remediation and some of the challenges it presents.

THC Remediation: A Basic Understanding

Lo Friesen is the founder, CEO, and Chief Extractor of Heylo. With a background in chemistry and clinical research, Lo was inspired to explore cannabis as a medicine and to enter the emerging industry. She joined Eden Labs, a leading CO

 extraction equipment manufacturer to support and expand a Research and Development department. There she managed the development of their latest and greatest CO

 extraction system. In 2017, after working with Eden Labs and another cannabis processor, Lo launched Heylo with a mission to help people get more out of life with cannabis.

This article explores the pros and cons of grinding cannabis prior to extraction along with the effects of particle size.

To Grind or Not To Grind

An interview with Dr. Bonni Goldstein on treating patients during a pandemic, telemedicine, cannabis research, and more.

Treating Immunocompromised Patients During the COVID-19 Pandemic:  A Conversation with Dr. Bonni Goldstein

A rapid LC–MS/MS method is presented for the quantitative analysis of 16 cannabinoids in hemp samples with a single dilution protocol.

Rapid Analysis of 16 Major and Minor Cannabinoids in Hemp Using LC–MS/MS with a Single Sample Dilution and Injection

is a Senior Scientist at Agilent Technologies and a Visiting Professor at The Johns Hopkins University School of Medicine in Baltimore, Maryland.

This article focuses on the use of GC–MS for the analysis of derivatized cannabinoids in hempseed oil matrix.

A Brief Review of Derivatization Chemistries for the Analysis of Cannabinoids Using GC–MS

A review of the chemical makeup of cannabis extracts and how they affect the human body. From terpenes to cannabinoids, this article takes a deep dive into the chemistry of cannabis extracts.

Exploring the Chemical Makeup of Cannabis Extract by Method

An interview with an amazing family of four doctors—the Knox Docs—who are key opinion leaders in cannabis therapeutics, endocannabinology, and cannabinoid medicine.

The First Family of Cannabinoid Medicine: The Knox Docs

A closer look at some of the current in vitro evidence suggesting that cannabinoids possess potent activity against a range of gram-positive bacteria.

The Role of Cannabinoids in the Global Fight Against Antibiotic Resistance 

Dr. Linda Klumpers discusses her interest in neuroscience, her most significant work, success stories from Cannify—an online science-matching tool—and more.

Cannabinoids + Clinical Pharmacology: A Q&A with Dr. Linda Klumpers

is an Application Scientists with Agilent Technologies in Wilmington, Delaware.

This study highlights a potential concern for the quantitation of acid phytocannabinoids.

The Stability of Acid Phytocannabinoids Using Electrospray Ionization LC–MS in Positive and Negative Modes

A large data set from Washington (140,000 flower samples) is scrutinized here for evidence of consistently propagated strains with higher than a 2-to-1 ratio.

Are There Limits to the Range of Possible Cannabinoid Ratios in Plants?

How to Choose the Right Instrumentation for Cannabinoid and Terpene Analysis

Brian C. Smith, PhD, is Founder, CEO, and Chief Technical Officer of Big Sur Scientific. He is the inventor of the BSS series of patented mid-infrared based cannabis analyzers. Dr. Smith has done pioneering research and published numerous peer-reviewed papers on the application of mid-infrared spectroscopy to cannabis analysis, and sits on the editorial board of Cannabis Science and Technology. He has worked as a laboratory director for a cannabis extractor, as an analytical chemist for Waters Associates and PerkinElmer, and as an analytical instrument salesperson. He has more than 30 years of experience in chemical analysis and has written three books on the subject. Dr. Smith earned his PhD on physical chemistry from Dartmouth College. Direct correspondence to: 

Applications of a quantitative mid-infrared spectrometer for hemp farmers, hemp extractors, state regulators, and law enforcement are discussed.

Quantitation of Cannabinoids in Dried Ground Hemp by Mid-Infrared Spectroscopy

A review of the literature to examine the analgesic properties of cannabis.

Medical Cannabis for Analgesia: Growth and Development

Dr. Andrea Holmes discusses how she’s using colorimetric analysis to discover novel minor cannabinoids, the potential role of smartphone compatibility in detection, what’s next for cannabinoid research, and more.