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Why Mandated Methods for Limit of Detection Determination Do Not Work
Why Mandated Methods for Limit of Detection Determination Do Not Work

August 28th 2025

Conventional approaches for determining limits of detection (LOD), such as signal-to-noise ratios and repeated measurement methods designed for single-signal detection, can result in unrealistic LOD values because they often fail to account for multi-signal identification and the disproportionate generation of analyte and noise signals in mass spectrometry techniques such as selected ion monitoring (SIM) and multiple reaction monitoring (MRM). This article proposes a practical alternative compared to standard approaches.

Best of the Week: April 18– April 24, 2025
Best of the Week: April 18– April 24, 2025

April 25th 2025

A Consumer Trends Survey of Minor Cannabinoids
A Consumer Trends Survey of Minor Cannabinoids

March 6th 2025

Expanding the Panel of Heavy Metals in Cannabis Consumer Products Beyond the Big Four: Understanding the Cost Difference
Expanding the Panel of Heavy Metals in Cannabis Consumer Products Beyond the Big Four: Understanding the Cost Difference

December 20th 2024

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