Automating your solid-state screening process enables you to perform the crystallization experiments with just a small amount of effort. Both CrystalBreeder and Crystal16 are the perfect tools for determining solubility in an easy and efficient manner. The solubility of your compound in organic solvents or water plays an important role when designing a crystallization screen. Knowing the solubility will allow you to select suitable solvents for the different crystallization methods.