App Notes

An HPLC method for the testing of CBD oils. The DLC-10 is a small footprint, easy-to-use and low-cost HPLC system. An isocratic assay offers reliability and ease of use.

PolyScience DuraChill® Technology: An overview of maintenance mitigation systems, chiller performance, and user ergonomics meeting the needs of the cannabinoid-extraction market.

Due to the legalization of cannabis and the associated legislation concerning trace metal analysis the demand for fast and easy-to-use acid digestion techniques is increasing. HVT vessels with SMART VENT Technology enable the convenient and reliable digestion of cannabis-based products prior to spectroscopic analysis.

This application note demonstrates a simple way to test the CBD and THC in Cannabis Extraction industry by PERSEE HPLC with a simple configuration, isocratic pump and UV detector.

Note discusses pesticide screening and testing using the QuEChERS method and LCMSMS. 

• Cannabinoid analysis • Herbicide/pesticide detection and quantification • Mycotoxin detection and quantification

Producing accurate measurements are vital for any process. To get the most accurate results, it is crucial to place your balance in a stable environment.

An HPLC method for the testing of CBD oils. The DLC-10 is a small footprint, easy-to-use and low-cost HPLC system. An isocratic assay offers reliability and ease of use.

For companies designing cannabis processing or post-processing systems, meeting the needs of the cannabinoid-extraction market means properly sizing and integrating components suited for 24/7 operation under adverse conditions.

Patient and consumer safety is a critical factor during manufacturing of your products. In addition, false test results in product quality testing can lead to unnecessary scrapping of batches and product recalls. Good pipetting practices using filtered and pure pipette tips help ensure contamination-free pipetting to prevent contamination during sample preparation, ensuring true test results and patient and consumer safety

The demand for fast and easy-to-use acid digestion techniques is increasing. HVT vessels with SMART VENT Technology enable the convenient and reliable digestion of cannabis-based products prior to spectroscopic analysis.

Preventing contamination in pipetting is paramount to achieving reliable results. It requires identification of the potential contamination mechanism in order that they can all be addressed. This paper addresses the three contamination types that originate from pipetting: Pipette-to-sample contamination, sample-to-pipette contamination, and sample-to-sample contamination. Keep in  mind: If your testing procedure in your Cannabis environment  requires you to repeatedly portion out exact volumes of liquids involved, our bottle-top dispensers will give you a steady hand to ensure accurate and consistent results.

Improving your HPLC Sample Preparation is easier than ever with the Sartorius Cubis® MSA Dosing System. The Cubis MSA individual system with Q-App software automatically corrects the solvent volume to the appropriate value, eliminating the need to reach the precise target weight. At the end of the procedure, the weight of the compound(s) and solvents is used to calculate the verified concentration(s) and the verified volume of the standard prepared.

We tested the novel filter device Claristep® for the preparation of protein samples containing one of four different target molecules: an anti-malaria vaccine candidate, aviscuminum, interferon alfa-2B, or monoclonal antibody (mAb) P2G12. In comparison to the standard protocols for sample preparation prior to analysis by either reversed-phase or SEC HPLC, the Claristep® filter did not exhibit a significant difference in protein concentration if the target molecules were present with at least 1.0 g L-1. A significantly reduced product concentration was observed in the Claristep® filtered samples compared to the standard protocol for mAb P2G12 if the concentrations were lower. The protein adsorption to the filter material was well described by a Langmuir adsorption isotherm. Additionally, the Claristep® filters facilitated a rapid sample preparation with minimal volume losses.

The two-fold objective of this study was to 1) demonstrate that aqueous mobile phase preparations from purchased lab grade bottled water yielded comparable results to in-house prepared water (Sartorius Arium purified water Type 1 and Type 3) and that 2) using filters (Sartorius Minisart RC, SRP, NY & NY Plus, all 0.2 µm) yielded comparable results to unfiltered specimens under the same mobile phase conditions.

This application note demonstrates a simple way to test the heavy metals in cannabis using PERSEE’s PF7 heavy metal analyzer. Compare it with ICP/ICP-MS: you still can achieve lower detection limit, better repeatability with significant lower running cost, and simpler operation.

High-quality reference materials with established metrological traceability are an essential element for measurement accuracy during routine analytical checks as well as for cannabis product quality testing and profiling. We compare two different methods using CRMs to generate a standard for the quantitation of 10 prevalent phytocannabinoids against a calibration curve to show that premade multicomponent CRM mixtures improve quantitation accuracy.

This application report demonstrates the suitability of HVT vessels with SMART VENT Technology for convenient and reliable digestion of cannabis-based products prior to spectroscopic analysis.

This application note demonstrates the CEM MARS 6 for microwave digestion of mixed cannabis and hemp containing products in a single run and elemental analysis of these products.

Pre-made, multicomponent CRM mixtures save time and consumable cost in the preparation of standard curves and improve quantitation accuracy.

This application note outlines a QuEChERS method for the analysis of hemp for three cannabinoids. Sample purification is carried out using UCT’s new cleanup product SpinFiltr™.

• Tips for mobile phase filtration • Answers to FAQs about syringe filter selection • Why filtration is so important to method development and sample prep • Filters for sample prep in dissolution testing

This application note demonstrates rapid automated extraction and LC and GC analysis of more than 400 pesticides from cannabis flower.

This application note demonstrates the performance of the CEM MARS 6 for digestion of mixed cannabis containing products in a single run for elemental analysis.